10/21/2018

Charcot Joints

Charcot Joints

Charcot joints occur when the ability to sense deep pain is lost or diminished. As a result of the inability to sense pain, small fractures begin to develop in areas of stress such as the arch of the foot. The normal response to a fracture is swelling and increased blood flow (reflex vasodilatation) to the affected area of bone. The increase in blood flow tends to 'wash away' calcium from the fracture site, resulting in weakening of the bone as well as more fractures. If the normal defensive device, pain, remains absent, a cycle of increasing fracture activity starts with progressive collapse of the supporting bone.

The description of Charcot joints dates back to be able to 1703 when neuropathic osteoarthropathy was first described by W. Musgrave. Charcot is credited regarding his work in 1868 for describing gait anomalies of patients with syphilis (tabes dorsalis). Jordan, in was the first to describe a relationship of diabetes to neuropathic arthropathy.

  • The most typical area of the foot to be effected by a Charcot joint could be the middle of the arch.
  • Charcot joints can also develop on the rearfoot and ankle but are much less common.
  • One of the most common cause of Charcot joints of the foot is peripheral neuropathy due to diabetes mellitus.

The progress of a Charcot joint could be rapid and is dependent upon several variables. Any ability to perceive pain may lead to a more prompt diagnosis because of patient's concern concerning their abilities to complete an average day. Full loss of deep pain sensation may delay early diagnosis. Charcot joints are easily confused with osteoarthritis, which can be treated much less aggressively than a Charcot joint.

1966 Eichenholz proposed a category of Charcot joints which is broken down into three distinctive stages. Stage one, or the development stage, shows debris surrounding the joints on xray. Stage one can develop over a period of days to weeks and it is radiographic change that occurs in response to unperceived trauma. Stage two is the coalescence stage. In stage two, the bone actually starts to heal with intake of debris and healing of large fracture fragments. Stage three, often called the reconstruction or reconstitution stage, note a reduction in bone turn over and reformation of stable bone structure. Stage 0 was added in 1999 by Sella and Barrette to include patients who exhibit clinical signs of Charcot arthropathy but have yet to show radiographic changes.

  • The classification proposed by Brodsky in 1992 includes the location of the Charcot joint and it is commonly used in clinical practice these days.
  • Brodsky's classification is as follows;

Type 1 - Lisfrank's joint - 27-60% of all Charcot joint deformities of the feet.

Type 3A - Ankle joint - 9% of all Charcot deformities.

Type 3B - the Posterior Calcaneus.

Type 4 - Multiple instances of the base and/or ankle.

Type 5 - the Forefoot.

Charcot joints are often not diagnosed until they produce another problem that has an effect on a patients normal actions. These may be as simple as a good inability to fit into shoes, or as severe as an infected ulceration of the foot. By this stage, the Charcot deformity has in all likelihood progressed to a point where there is massive displacement of the bones and joints together with multiple displaced fractures.

  • Any problem that plays a role in the loss of sensation of the foot may be considered a cause for a Charcot combined.
  • Some of the people conditions include;

Diabetes mellitus Tabes dorsalis (neuropathy caused by syphilisHansen's Disease (Leprosy) Tumors of the spinal cordDegenerative change from the spinal cord or peripheral nerveAmyloid Familial-hereditary neuropathies including Charcot-MarieToothe Disease, Hereditary sensory neuropathy andDejerine-Sottas Illness Pernicious Anemia.

Injectable and systemic use of steroids PhenylbutazoneIndomethacin Vincristine

Other factors that may contribute to producing neuropathy, and subsequently, Charcot joints include;

Alcoholic neuropathy Hereditary insensitivity to pain Pott'sDisease (tuberculosis of the spine)

The most common complicating factor of a Charcot joint of the foot is the prominence that grows on the bottom of the foot, referred to as a 'rocker bottom' foot. This problem occurs as the bones of the arch collapse. In an advanced rocker bottom foot, the inability to feeling pain becomes a complicating factor for the skin. As the bone places a lot more pressure on the skin, the skin begins to ulcerate and becomes infected.

X-rays will be the single most useful tool in diagnosing Charcot joints. Bone scans are helpful in the early phases of Charcot joints and are sensitive indicators of hyperemia (increased blood flow to the area of the fracture). Surface skin temperature is probably the most reliable indicator of the activity of the fractures. Most doctors do not keep the necessary equipment to measure skin temperature but merely measure with direct touch in order to sense the presence or lack of warmth.

Treatment of Charcot Joints

The hallmark of treatment of Charcot joints is early diagnosis and prevention. The symptoms and findings of Charcot joints vary so that each case requires careful evaluation. Therapy ofCharcot joints of the feet may include rest, throwing and non-weight bearing to allow adequate time for fracture healing. Total contact casting or the use of a Charcot Restraint OrthoticWalker (CROW) are usually wellliked in stages one and two. The goal is to limit weight bearing to enable progression to stage three. This particular progression can take from weeks around 6 months. Electrical stimulation, or perhaps bone stimulation, is a trendy adjunct in order to non-weight bearing or sending your line.

Surgical procedures for Charcot joints are often challenging not only due to the complexity of this condition but also due to the fact that these patients are usually poor surgical candidates due to other health problems (co-morbidity). Surgical procedure may include reconstruction of the arch and/or shared fusion. Often, surgical procedures are used to go back the foot to a shape that can be accommodated by normal foot wear. Stage threeCharcot deformities often result in lumps, bump and unusually shaped feet as a result of bone fragments changes. Reshaping the base may be used to eliminate a boney prominence on the top or bottom of the foot.

Nomenclature: reflex vasodilitation - increased flow of blood to an area inside response to inflammation

Rocker bottom foot - a prominence which forms on the sole or even bottom with the foot as a result of the collapse from the arch

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  • Symptoms:

    The symptoms of Charcot joints vary based upon the location and severity of the situation. The first sign is localized edema swelling) of the joint or joint parts. The edematous area may exhibit increased temperature change. Often, the first apparent indicator that a patient with advanced sideline neuropathy will notice is the fact that their shoes have become tighter or they will have a problem appropriate into a pair of shoes that have fit well for some time.

    The challenge in diagnosing this condition is the lack of signs that are due to peripheral neuropathy. Peripheral neuropathy makes it impossible for the patient to be able to speak in terms that would be understood by the general population such as 'my toes hurt'. As a result, the physician needs to rely more on testing and less on the history and physical exam.

    Differential Diagnosis:

    The differential diagnosis for this condition should include;

    • Bone tumor.
    • Fracture.
    • Idiopathic edema
    • Pseudogout.
    • Soft tissue tumor

    Additional References Include;

    Grady, J.F., et al: The use of electrostimulation in the treatment of diabetic neuroarthropathy J. Am. Podiatric Med. Assoc. 90(6): 287-294, 2000

    Gout Update

    2TKLXPs-FeI

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    About the actual author:Jeffrey A. Oster, DPM, C.Ped is a board certified foot and ankle surgeon. Dr. Oster can be board certified in pedorthics. Dr. Oster is medical director of Myfootshop.com and is in active practice in Granville, Ohio.

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